RESOURCES AND ORGANIZATIONS

NAMI Connection Recovery Support Group

www.nami.org

NAMI Connection is a weekly recovery support group for people living with mental illness in which people learn from each others' experiences, share coping strategies, and offer each other encouragement and understanding. Find a support group near you.

Depression and Bipolar Support Alliance (DBSA)

www.dbsalliance.org

730 N. Franklin Street, Suite 501
Chicago, IL 60654-7225
800-826-3632

The Depression and Bipolar Support Alliance (DBSA) is a patient-directed national organization focusing on the most prevalent mental illnesses. The organization fosters an environment of understanding about the impact and management of these illnesses by providing up-to-date, scientifically based tools and information written in language the general public can understand. DBSA supports research to promote more timely diagnosis, develop more effective and tolerable treatments, and discover a cure. The organization works to ensure that people living with mood disorders are treated equitably. DBSA was founded in 1985.

Families for Depression Awareness

www.familyaware.org

395 Totten Pond Road, Suite 404
Waltham, MA 02451
781-890-0220

Families for Depression Awareness helps families recognize and cope with depressive disorders. The purpose of this organization is to help families recognize and manage the various forms of depression and associated mood disorders, reduce stigma associated with depressive disorders, and unite families and help them heal in coping with depression.

Families for Depression Awareness offers a unique tool called the Mental Health Family Tree Builder. After completing a simple questionnaire, you can print an easy-to-read "family tree" that maps the existence of behaviors associated with bipolar disorder in your family. You can then share this family tree with your doctor or family. This builder is completely anonymous, and your personal information will not be saved.

The Jed Foundation

www.jedfoundation.org

220 Fifth Avenue, 9th Floor
New York, NY 10001
212-647-7544

The Jed Foundation was founded in 2000 by Phil and Donna Satow after they sadly lost their 20-year-old son, Jed, to suicide. The Jed Foundation is a New York–based 501(c)(3) charitable organization with a mission to reduce the suicide rate among college and university students across the United States.

The organization's major initiatives are rooted in its widely distributed "Prescription for Prevention" model, which defines a comprehensive suicide prevention and mental health promotion framework for colleges and universities. Its programs, informed by both clinical and public health perspectives, target the full range of audiences who can influence college mental health, including students, colleges, politicians, mental health professionals, and parents. Its work involves fostering greater public awareness of the extent of college-age suicides, collaborating with colleges and universities to strengthen mental health services on campus, creating linkages between the academic research community that works on suicide prevention and the higher education professionals who work directly with students, and producing innovative Internet-based intervention systems for college students.

MedlinePlus

www.nlm.nih.gov/medlineplus

MedlinePlus will direct you to information to help answer health questions. MedlinePlus brings together authoritative information from the National Library of Medicine, the National Institutes of Health, and other government agencies and health-related organizations. Preformulated Medline searches are included in MedlinePlus and provide easy access to references to medical journal articles. MedlinePlus also has extensive information about drugs and supplements, an illustrated medical encyclopedia, interactive patient tutorials, the latest health news, and surgery videos.

Mental Health America (MHA)

www.nmha.org

2000 N. Beauregard Street, 6th Floor
Alexandria, VA 22311
800-969-6MHA (6642)

Mental Health America (formerly known as the National Mental Health Association) is dedicated to helping people live mentally healthier lives. With more than 320 affiliates nationwide, MHA represents a growing movement of Americans who promote mental wellness for the health and well-being of the nation—every day and in times of crisis.

National Alliance on Mental Illness (NAMI)

www.nami.org

3803 N. Fairfax Dr., Suite 100
Arlington, VA 22203
800-950-NAMI (6264)

NAMI is the nation's largest grassroots mental health organization dedicated to improving the lives of both persons living with serious mental illness and their family members. Founded in 1979, NAMI has become a prominent national voice on mental illness. NAMI organizations in every state and in over 1,100 local communities across the country join together to advance the NAMI mission through advocacy, research, support, and education.

National Hopeline Network

www.hopeline.com

800-SUICIDE (784-2433)

The Kristin Brooks Hope Center (KBHC), along with its primary program, the National Hopeline Network, is a nonprofit organization dedicated to suicide prevention, intervention, and healing. The organization accomplishes this by providing a single point of entry to community-based crisis services through innovative telephone- and Internet-based technologies; by bringing national attention and access to services for postpartum depression and other women's mood disorders; through education and advocacy; through formal research and evaluation of crisis line services; and by championing the need for national funding for community-based suicide prevention crisis services.

National Institute of Mental Health (NIMH)

www.nimh.nih.gov

6001 Executive Boulevard, Room 8184, MSC 9663
Bethesda, MD 20892-9663
866-615-6464

The National Institute of Mental Health (NIMH) is one of 27 components of the National Institutes of Health (NIH), the federal government's principal biomedical and behavioral research agency. NIH is part of the US Department of Health and Human Services. The NIMH mission is to reduce the burden of mental illness and behavioral disorders through research on mind, brain, and behavior. This public health mandate demands that the institute harness powerful scientific tools to achieve better understanding, treatment, and, eventually, prevention of these disabling conditions that affect millions of Americans.

The information on this Web site should not take the place of talking with your doctor or health care professional. If you have any questions about your condition, or if you would like more information about Seroquel XR, talk to your doctor or pharmacist. Only you and your health care professional can decide if Seroquel XR is right for you.

Important Safety Information and Indications for Seroquel XR and Seroquel

Elderly patients with dementia-related psychosis (having lost touch with reality due to confusion and memory loss) treated with this type of medicine are at an increased risk of death, compared to placebo (sugar pill). Seroquel XR and Seroquel are not approved for treating these patients.

Antidepressants have increased the risk of suicidal thoughts and actions in some children, teenagers, and young adults. Patients of all ages starting treatment should be watched closely for worsening of depression, suicidal thoughts or actions, unusual changes in behavior, agitation, and irritability. Patients, families, and caregivers should watch for these symptoms and report them immediately to the doctor. Seroquel XR is not approved for patients under the age of 18 years. Seroquel is not approved for patients under the age of 10 years.

A rare, but potentially fatal, side effect reported with Seroquel XR, Seroquel, and medicines like them is neuroleptic malignant syndrome (NMS). Tell your doctor if you have very high fever; rigid muscles; shaking; confusion; sweating; changes in pulse, heart rate, or blood pressure; or muscle pain and weakness because treatment should be stopped if you have NMS
High blood sugar and diabetes have been reported with Seroquel XR, Seroquel, and medicines like them. If you have diabetes or risk factors such as obesity or a family history of diabetes, your doctor should check your blood sugar before you start taking Seroquel XR or Seroquel and also during therapy. If you develop symptoms of high blood sugar or diabetes, such as excessive thirst or hunger, increased urination, or weakness, contact your doctor. Complications from diabetes can be serious and even life threatening
Increases in triglycerides and in LDL (bad) cholesterol and decreases in HDL (good) cholesterol have been reported with Seroquel XR and Seroquel. Your doctor should check your cholesterol levels before you start Seroquel XR or Seroquel and during therapy
Weight gain has been reported with Seroquel XR and Seroquel. Your doctor should check your weight regularly
Tell your doctor about any movements you cannot control in your face, tongue, or other body parts, as they may be signs of a serious condition called tardive dyskinesia (TD). TD may not go away, even if you stop taking Seroquel XR or Seroquel. TD may also start after you stop taking Seroquel XR or Seroquel
Other risks include feeling dizzy or lightheaded upon standing, or having trouble swallowing. Tell your doctor if you experience any of these
Increases in blood pressure have been reported with Seroquel in children and teenagers. Your doctor should check blood pressure in children and adolescents before starting Seroquel and during therapy
Before starting treatment, tell your doctor if you have or have had low white blood cell (WBC) count, seizures, abnormal thyroid tests, high prolactin levels, heart or liver problems, or cataracts. An eye exam for cataracts is recommended at the beginning of treatment and every 6 months thereafter
Since drowsiness has been reported with Seroquel XR and Seroquel, you should not participate in activities such as driving or operating machinery until you know that you can do so safely. Avoid becoming overheated or dehydrated while taking Seroquel XR or Seroquel. Do not drink alcohol while taking Seroquel XR or Seroquel
Tell your doctor if you are pregnant or intend to become pregnant. Avoid breast-feeding while taking Seroquel XR or Seroquel
Common side effects: For Seroquel XR, the most common side effects in adults are drowsiness, dry mouth, constipation, dizziness, increased appetite, upset stomach, weight gain, fatigue, disturbance in speech and language, and stuffy nose. For Seroquel, the most common side effects in adults are drowsiness, dry mouth, dizziness, constipation, weakness, abdominal pain, a sudden drop in blood pressure upon standing, sore throat, weight gain, sluggishness, abnormal liver tests, and upset stomach. The most common side effect in children and adolescents are drowsiness, dizziness, fatigue, increased appetite, nausea, vomiting, dry mouth, rapid heartbeat, and weight gain

This is not a complete summary of safety information. Please discuss the full Prescribing Information for both products with your health care provider.

Indications

Seroquel XR is a once-daily tablet approved in adults for (1) add-on treatment to an antidepressant for patients with major depressive disorder (MDD) who did not have an adequate response to antidepressant therapy; (2) acute depressive episodes in bipolar disorder; (3) acute manic or mixed episodes in bipolar disorder alone or with lithium or divalproex; (4) long-term treatment of bipolar disorder with lithium or divalproex; and (5) schizophrenia. Seroquel is approved for (1) depressive episodes in bipolar disorder in adults; (2) manic episodes in bipolar disorder in adults when used alone or with lithium or divalproex; (3) manic episodes in bipolar disorder in children and adolescents ages 10 to 17 years; (4) long-term treatment of bipolar disorder in adults with lithium or divalproex; (5) schizophrenia in adults and (6) schizophrenia in adolescents ages 13-17 years.

Click here to see the Prescribing Information for Seroquel XR, including Boxed Warnings.

Click here to see the Medication Guide for Seroquel XR.

Click here to see the Prescribing Information for Seroquel, including Boxed Warnings.

Click here to see the Medication Guide for Seroquel.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

Patient photos are intended to be representative of typical patients with bipolar disorder and are not of actual patients.