Treating bipolar disorder

Treatment options are available for bipolar disorder

If you're still living with symptoms of bipolar disorder, you should know that many people with the condition are able to manage their symptoms. Feeling better often involves a combination of education, medication, and therapy, including psychotherapy, or "talk therapy." There are a number of different medications that have been shown to be effective in people with bipolar disorder, including SEROQUEL XR.

Some of the goals of bipolar disorder treatment

  • Reduce symptoms of depressive episodes
  • Reduce symptoms of manic episodes
  • Provide assistance and support to patients and family

Bipolar disorder medication options

Many types of medications are used to treat bipolar disorder. One medication approved to treat bipolar disorder is SEROQUEL XR. Learn more about SEROQUEL XR.

Your doctor can tell you what kinds of improvements and potential side effects you may expect with SEROQUEL XR. It may take some time before you start to feel better, but by finding a treatment that works for you, and taking it as prescribed, you can work toward getting back to the things you once enjoyed.

Your health care professional will depend on you to let him or her know exactly how you are feeling, so your treatment can be adjusted, if needed. Use these questions to ask your doctor to help prepare for your next appointment.

Psychotherapy (talk therapy) for bipolar disorder

Psychotherapy (also called talk therapy) can make it easier for patients and families to cope with disturbing thoughts, feelings, and behaviors associated with bipolar disorder. Talk therapy focuses on several important aspects of bipolar disorder management, including:

  • Recognition of and treatment for recurrent mood episodes
  • Management of stress, interpersonal/family issues, and regularity of daily activities
  • Development of problem-solving skills

Psychotherapy can be used in combination with medication and other treatment approaches. Find out more about living with bipolar disorder.

Important Safety Information About SEROQUEL XR® (quetiapine)Read More +

  • Elderly patients with dementia-related psychosis (having lost touch with reality due to confusion and memory loss) treated with this type of medicine are at an increased risk of death, compared to placebo (sugar pill). SEROQUEL XR is not approved for treating these patients...
Living with bipolar disorder >
US-25490; US-40332; US-45751 Last Updated 10/20

Important Safety Information About SEROQUEL XR® (quetiapine)


Elderly patients with dementia-related psychosis (having lost touch with reality due to confusion and memory loss) treated with this type of medicine are at an increased risk of death, compared to placebo (sugar pill). SEROQUEL XR is not approved for treating these patients.

Antidepressants have increased the risk of suicidal thoughts and actions in some children, teenagers, and young adults. Patients of all ages starting treatment should be watched closely for worsening of depression, suicidal thoughts or actions, unusual changes in behavior, agitation, and irritability. Patients, families, and caregivers should pay close attention to any changes, especially sudden changes in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed. These symptoms should be reported immediately to the doctor. SEROQUEL XR is not approved for children under the age of 10 years.

    Do not take SEROQUEL XR if you are allergic to quetiapine or any of the ingredients in SEROQUEL XR.

    Stroke that can lead to death can happen in elderly people with dementia who take medicines like SEROQUEL XR.

    Stop SEROQUEL XR and call your doctor right away if you have some or all of the following symptoms: high fever; excessive sweating; stiff muscles; confusion; changes in pulse, heart rate, and blood pressure. These may be symptoms of a rare, but very serious and potentially fatal, side effect called neuroleptic malignant syndrome (NMS).

    High blood sugar and diabetes have been reported with SEROQUEL XR and medicines like it. If you have diabetes or risk factors such as obesity or a family history of diabetes, your doctor should check your blood sugar before you start taking SEROQUEL XR and also during therapy. If you develop symptoms of high blood sugar or diabetes, such as excessive thirst or hunger, increased urination, or weakness, contact your doctor. Complications from diabetes can be serious and even life threatening.

    Increases in triglycerides and in LDL (bad) cholesterol and decreases in HDL (good) cholesterol have been reported with SEROQUEL XR. Your doctor should check your cholesterol levels before you start SEROQUEL XR and during therapy.

    Weight gain has been reported with SEROQUEL XR. Your doctor should check your weight regularly.

    Tell your doctor about any movements you cannot control in your face, tongue, or other body parts, as they may be signs of a serious condition called tardive dyskinesia (TD). TD may not go away, even if you stop taking SEROQUEL XR. TD may also start after you stop taking SEROQUEL XR.

    Other risks include feeling dizzy or lightheaded upon standing, falls (which may cause serious injuries), trouble swallowing, or decreases in white blood cells (which can be fatal). Fever, flu-like symptoms, or any other infection could be a result of a very low white blood cell count. Tell your healthcare provider as soon as possible if you experience any of these.

    Increases in blood pressure have been reported with SEROQUEL XR in children and adolescents. Your doctor should check blood pressure in children and adolescents before starting SEROQUEL XR and during therapy.

    Before starting treatment, tell your doctor about all prescription and nonprescription medicines you are taking. Also tell your doctor if you have or have had low white blood cell count, seizures, abnormal thyroid tests, high prolactin levels, heart or liver problems, trouble emptying your bladder, enlarged prostate, constipation, increased pressure inside your eyes, or cataracts. An eye exam for cataracts is recommended at the beginning of treatment and every 6 months thereafter.

    Since drowsiness has been reported with SEROQUEL XR, you should not participate in activities such as driving or operating machinery until you know that you can do so safely. Avoid becoming overheated or dehydrated while taking SEROQUEL XR. Do not drink alcohol while taking SEROQUEL XR.

    Tell your doctor if you are pregnant or intend to become pregnant. Avoid breastfeeding while taking SEROQUEL XR.

    The most common side effects in adults are drowsiness, dry mouth, constipation, dizziness, increased appetite, upset stomach, weight gain, fatigue, difficulty moving, and disturbance in speech or language, and stuffy nose. The most common side effects in children and adolescents are drowsiness, dizziness, fatigue, stuffy nose, increased appetite, upset stomach, vomiting, dry mouth, rapid heartbeat, and weight gain.

    Do not stop taking SEROQUEL XR without talking to your doctor. Stopping SEROQUEL XR suddenly may cause side effects.

This is not a complete summary of safety information. Please discuss the full Prescribing Information with your health care provider.

Approved Uses

SEROQUEL XR is a once-daily tablet approved in adults for (1) add-on treatment to antidepressants for patients with major depressive disorder (MDD) who did not have an adequate response to antidepressant therapy; (2) acute depressive episodes in bipolar disorder; (3) acute manic or mixed episodes in bipolar disorder alone or with lithium or divalproex; (4) long-term treatment of bipolar disorder with lithium or divalproex; and (5) schizophrenia. SEROQUEL XR is also approved for (6) acute manic episodes in bipolar disorder in children and adolescents ages 10-17 years; and (7) for schizophrenia in adolescents ages 13-17 years.

Please read the Medication Guide and full Prescribing Information, including Boxed WARNINGS.

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This site is intended for US customers only.

The information on this Web site should not take the place of talking with your doctor or health care professional. If you have any questions about SEROQUEL XR, talk to your doctor or pharmacist. Only you and your health care professional can decide if SEROQUEL XR is right for you.